Schematische weergave van de dubbele helix (wentelttrap) in DNA.

Written sources from before 1500 are scarce. For Dutch people with an immigrant background, this already applies to written sources from a much later date. In that case DNA research can offer a solution. This may involve tracing early ancestors or determining the degree of kinship between persons still alive. DNA testing can also be valuable in situations where a written source is not considered to be sufficiently reliable.

DNA types

There are two types of DNA. The most important is the DNA present in the nucleus of every human cell. This DNA consists of 23 chromosome pairs. One is the so-called sexual chromosome pair. In case of a man this consists of a Y and an X chromosome and in a case of a woman of two X chromosomes. The remaining 22 chromosome pairs together are called the autosomes (non-sexual chromosomes).

There is not only DNA in the nucleus of a cell, but also in the mitochondria, althought to a much lesser extent. Mitochondria are organelles that are present in the plasma of a cell. They take care of the energy supply of a cell. The DNA in these organelles is called mitochondrial DNA and, for the sake of brevity, mt-DNA.

Research based on Y-DNA

Webmaster Peter van Boheemen took a first step in 2007 by participating in the Dutch project ‘Sons of Adam in the Netherlands’ (see Publications). A second step followed in 2017 by participating in a comparative study together with four other male members of the Van Bohe(e)men family.

Both tests relate to the DNA in the Y-chromosome (Y-DNA). It benefits from the fact, that a son basically has the same Y-DNA as his father. Therefor every present-day man should have the same Y-DNA as the most recent common forefather of all present-day men. This forefather is called Y-chromosomal Adam. He lived in Africa 150,000-300,000 years ago. At that time he was not the first and also not the only man, but we may say he was the only man who has still descendants in the world today.

When Y chromosomes are reproduced, however, there may occur a small error which is passed on to descendants. Such mutations explain that there are differences between present-day families in composition of the Y-DNA.

The five male family members who participated in the comparative DNA tests have a common forefather born around 1760. The test results demonstrate that all five participants have the same mutations in the Y-DNA. This proves the five are not only related to each other in a legal sense, but also in a biological sense. At the same time, the comparative DNA tests reinforce the reliability of the family tree created (and also the family feeling among the participants).
Additional tests with participation of male family members from previously split-off family branches can further enhance the accuracy of the family tree. If there is interest in participation, let us know. This can be done using the Contact Form.

Based on worldwide research on human fossils, it has since been determined for many mutations where and when they took place. This makes it possible to trace the route traveld by the descendants of Y-chromosomal Adam.

Webmaster Peter van Boheemen has a series of mutations classified as haplogroup R1b-L48. His descent of Y-chromosomal Adam is presented in the following overview.

On the left side of the overview the generation numbers of different forefathers are mentioned. Y-chromosomal Adam has generation number 1. For the sake of convenience, it is assumed that he was born in Africa 230,000 years ago, given the bandwidth in the estimated period of his life. At the bottom of the overview, webmaster Peter van Boheemen is mentioned with generation number 6900. Number 6900 is based on the assumption that, on average, three male generations occur in a century. For a period of 230,000 years, this amounts to 6900 generations.

Patrilinearity of webmaster Peter van Boheemen from Y-chromosal Adam (National Genographic).

Under Y-chromosomal Adam, mutation P305 is mentioned in the overview. This mutation took place in Africa about 100,000 years ago. It is the earliest mutation that does not occur in all present-day men and is therefore seen as the first split off in the male pedigree.

The later mutation P143 marks a crucial moment. It is namely a mutation that occurred outside of Africa. It happened to a forefather who lived 60,000 years ago in the Middle East (Saudi Arabia). He belongs to the group that left Africa shortly before due to drought and followed wildlife to greener, more northern areas. It is likely there has been crossed  from present-day Ethiopia to the Arabian peninsula.

Between 45,000 and 20,000 years ago, the forefathers, roughly speaking, migrated to Russia via Afghanistan, West China and Kazakhstan. Less than 4600 years ago, migration to Western Europe coincided with the spread of agriculture. About 700 years or more ago, the then forefathers settled on the border of the current municipality of The Hague with the current municipality of Westland. The overview ends with webmaster Peter van Boheemen who was born a short distance away in 1950.

A more detailed analysis will no doubt be possible in the near future

Spread of Y-haplogroup R1b-L48  to which webmaster Peter van Bohemen belongs (National Genographic)

Postscript (same for mt-DNA)
Two male persons with the same setries of mutations in their Y-DNA do not necessarily belong to the same present-day family. The most recent mutation may have occurred thousands of years ago. The forefather wihere the most recent mutation occurred is the common forefather. Apparently, several present-day families emerged later from his descendants.
For example, the aforementioned project “Sons of Adam” demonstrated that webmaster Peter van Boheemen has the same series of mutations as another participant. The two patrilinearities that go back to around 1500, however, have no agreement. All this means that another indication (for example, a written archive source) is required to prove a close relationship, in addition to an agreement in the series of mutations in the Y-DNA.

Research based on mt-DNA

Special is that the mitochondria of a child contains the same DNA as those of the mother. The mt-DNA of the father is not passed on.

In mt-DNA mutations occur occasionally, just like in Y-DNA. This makes it possible to trace someone’s foremothers on the basis of mt-DNA. In this way there can also be determined on the whether a legal female pedigree based on written archive sources is also correct in the biological sense.

The mt-DNA of webmaster Peter van Boheemen has a series of mutations that are classified as haplogroup H1c. His descent of so-called mitochondrial Eve is shown in the following overview. Mitochondrial Eve, like Y-chromosomal Adam, is considered to be the most recent common foremother of all present-day women.

On the left side of the overview the generation number of different foremothers are mentioned. Mitochondrial Eva has the number 1 and the webmaster Peter van Boheemen mentioned at the end the number 8000. The number 8000 is based on the assumption that, on average, our female generations occur in a century. For a period of 200,000 years this comes to 8,000 generations

Matrilineality of webmaster Peter van Boheemen from mitochondrial Eve (National Genographic).

Mitochondrial Eve, like Y-chromosomal Adam, was neither the first nor the only woman at the time. She lived in the Old Stone Age in present-day Ethiopia, Kenya or Tanzania. She probably had dark skin (as protection against sunlight), dark hair and brown eyes. The fossils from southwestern Ethiopia (195,000 ± 5000 years BP) include a young woman with a height of 162-182 cm and a weight of approximately 70 kg.
Other fossils found near the human bones give an idea of ​​the way of life along the Omo river. The people ate fish, birds and anything else eatable that they could collect in the surrounding swamp, grassland and forest. They manufactured their utensils from flint and from the bones of birds and wild cattle.
At the time, it was much more humid in the Omo Valley than it is now because of the Saalian ice age, when the northern half of the Netherlands was covered with ice and the Veluwe embankments formed. The greater cold in the north led to more rain in Africa. The Salien lasted until around 126,000 years BP.

Under Eve in the overview, haplogroup L3 is mentioned which is characterized by a mutation taken place 67,000 years ago in East Africa. Then haplogroup N follows, which is based on a mutation occurred 60,000 years ago near the border between East Africa and Saudi Arabia. The members of haplogroup N, driven by drought in the Sahara, traveled through the Nile basin to Sinai.

Until 10,000 years ago, the foremothers resided in the Middle East. Afterwards they moved into Europe. About 300 years or more ago they settled in or near the current municipality of Leidschendam. The overview ends with webmaster Peter van Boheemen who was born a short distance away in 1950.

A more detailed analysis will no doubt become available in the near future.

Spread of mt-haplogroup H1c to which of webmaster Peter van Boheemen belongs (National Genograpic).

Research based on autosomal-DNA

In autosomal research all chromosomes are analysed, except the sexual chromosomes X and Y. For each person this results in a unique combination of DNA characteristics.

For people who are very closely related to each other, there is a large similarity in the DNA profile. However, the farther the relationship, the less similarity. This dilution is fast. As a result, research based on autosomal DNA is not (yet) suitable for demonstrating a distant relationship. In a child, half of the autosomal DNA comes from the father and the other half from the mother. This rule does not apply to earlier generations. A child does not receive 25% of the autosomal of every grandparent and 12.5% ​​of every great-grandparent. Of the 50% that a father passes on, 20% can come from his father and 30% from his mother. This is a consequence of the rearrangement of the autosomal DNA during the process of producing egg and sperm cells.

The rearrangement just mentioned explains that a person has barely any autosomal DNA of some of the 128 ancestors born eight generations earlier. As a result, only half of the ancestors  among those of ten generations ago are present in the autosomal DNA. Generally speaking, autosomal DNA can only be used to search for ancestors born after 1700. Therefor it is advisable to let participate  several family members, so a kinship can be approached from multiple sides.

The extent to which autosomal DNA matches, is expressed in the number of equal pieces of DNA and the total length thereof, measured in centimorgan (cM). There are tables indicating how many centimorgan may be expected in a certain family relationship such as a cousin or a great-uncle.

The autosomal DNA of webmaster Peter van Bohemen  has not yet been analysed. Therefor he has no experience yet with checking the similarities of his autosomal DNA with others in his family tree and tracing for him still unknown members of the Van Bohe (e) men family.

Research based on X-DNA

As mentioned earlier, a woman has two X chromosomes. One comes from her mother and the other from her father. A father only has one X chromosome, besides one Y chromosome.

When a father passes on his X chromosome to an descendant, he gets a daughter. All his daughters will receive the same X chromosome. DNA research based on X-DNA can therefore be used to determine whether two women descend from the same father.

A mother does not pass on one of her two X chromosomes to a child, but a mix of both X chromosomes. Two children of the same mother therefore do not receive an identical X chromosome. One way out is that two children of the same mother do have the same mt-DNA.

Sources:
– Theme DNA on website www.cbg.nl